Fame Host (https://fame.so) Neural Compass https://podcasts.fame.so/neural-compass-podcast https://feeds.fame.so/neural-compass-podcast Welcome to Neural Compass, a new podcast from Jimini Health. We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care. Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers. Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care. Learn more: jiminihealth.com 95a795e0-59a5-11f1-a62d-e317ef72e876 en Thu, 30 Apr 2026 11:57:48 +0000 Mon, 06 Jul 2026 15:07:36 +0000 https://content.fameapp.so/uploads/y31m7mz1/3e441e50-5dc2-11f1-af21-8b06bdc8f81e/3e442000-5dc2-11f1-bfa0-77a92b5a16ae.png Neural Compass https://podcasts.fame.so/neural-compass-podcast Welcome to Neural Compass, a new podcast from Jimini Health. We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care. Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers. Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care. Learn more: jiminihealth.com Jimini Health Welcome to Neural Compass, a new podcast from Jimini Health. We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care. Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers. Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care. Learn more: jiminihealth.com No No episodic Jimini Health Welcome to Neural Compass, a new podcast from Jimini Health. We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care. Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers. Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care. Learn more: jiminihealth.com Welcome to Neural Compass, a new podcast from Jimini Health. We’re charting the future of mental and behavioral health - at the intersection of AI, psychiatry, neuroscience, and real-world clinical care. Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next - from healthcare executives to AI pioneers. Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care. Learn more: jiminihealth.com Jimini Health team-jmh@fame.so No No No The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh https://podcasts.fame.so/e/rnklzpp8 The Measuring Gap: How AI and objective data are finally transforming psychiatric care, with Arpan & Amit Parikh 13 No No 70wj2ll1 You’ve likely heard that psychiatric progress is often stalled by subjective results. What is less understood is why the field remains slow to adopt in objective measurement even as other medical specialties thrive on hard data. Psychiatry faces a measurement gap. Dr. Arpan Parikh and Dr. Amit Parikh discusses measurement based Care, virtual health, and AI data synthesis. This is their honest account of why psychiatry must embrace measurement and how AI can finally bridge the clinical data gap. Join Marc Jacobstein on Neural Compass as he speaks with brothers and psychiatrists Dr. Arpan Parikh and Dr. Amit Parikh. They examine the historical resistance to Measurement-Based Care and why the field has often prioritized intuition over objective metrics. 

The discussion moves into the practicalities of treating complex serious mental illness through virtual care models. They also explore how AI can act as a superintelligence for clinicians by synthesizing vast amounts of patient data and automating the collection of collateral information from families. This episode breaks down how AI can do the administrative heavy lifting so psychiatrists can focus on what actually moves the needle in the room. 

What You’ll Learn

  • The psychological barriers preventing the adoption of Measurement-Based Care.
  • How virtual care models are successfully reaching underserved Medicaid populations.
  • The limitations of current clinical scales and the need for sophisticated data.
  • Methods for using AI to automate the gathering of collateral medical history.
  • Ways technology can synthesize fragmented patient records to improve visit impact.
  • The connection between mental health outcomes and the total cost of care reduction.

About the Guests 

Dr. Arpan Parikh is a double board-certified psychiatrist and the Chief Medical Officer at Soul Mental Health. He oversees clinical strategy for a multisite outpatient group and completed his residency at Mount Sinai.

Dr. Amit Parikh is a child and adolescent psychiatrist serving as the Chief Medical Officer at Brave Health. His work focuses on utilizing virtual care to treat complex and chronic patient populations within the Medicaid system.

Episode Highlights

[00:00:00] The Measurement Gap in Psychiatry 

Dr. Arpan Parikh notes that psychiatry has historically been late to adopt hard metrics compared to specialties like cardiology. He suggests that clinicians often believe their work is too special to be quantified by standard logic. This mindset must shift toward accepting that psychiatric treatment can and should be measured to ensure progress. Embracing measurement is a necessary evolution for the field to align with modern medical standards.

[00:09:44] Understanding Measurement-Based Care 

Dr. Amit Parikh defines Measurement-Based Care as the use of objective tools to track patient progress over time. While it is treated as a modern buzzword, it is actually the foundation of most medical fields. These tools provide extra data points rather than replacing the clinician's subjective expertise during a visit. Incorporating these measures allows for a more comprehensive understanding of the patient's journey toward their goals.

[00:15:39] The Over-Rotation to Clinical Scales 

While the push for measurement is positive, there is a risk of focusing too heavily on standard scales like the PHQ-9. Dr. Arpan Parikh argues that we must look beyond these simple questionnaires to more sophisticated data-gathering methods. This includes using technology to understand the nuances of a patient's daily life and behavioral patterns. Moving past basic forms will help clinicians avoid the pitfalls of a narrow data window.

[00:23:02] Virtual Care for Complex Populations 

Brave Health utilizes virtual platforms to reach Medicaid populations who often face significant barriers to in-person care. Dr. Amit Parikh emphasizes that these treatments are effective when care is made feasible for the patient to attend. Consistency in treatment remains the most significant driver of positive outcomes for serious mental illness. Virtual care allows organizations to meet patients where they are rather than expecting them to navigate complex transportation.

[00:31:41] AI as a Superpower for Clinicians 

AI tools offer a way to integrate diverse data sources into the initial clinical assessment for better accuracy. Dr. Arpan Parikh identifies collateral information from family members as a critical but manual task that technology could automate. This would allow psychiatrists to make more accurate differential diagnoses without adding to their administrative burden. Utilizing technology for these tasks creates a more efficient workflow for the entire clinical team.

[00:41:45] Synthesizing the Clinical Information Overload 

Medicine has become increasingly complex, making it difficult for clinicians to review every patient note and lab value. Dr. Amit Parikh describes a need for AI models that can provide concise summaries of events between visits. This capability would make each clinical encounter more impactful by ensuring the physician is fully informed of the patient's history. Synthesizing this data helps bridge the gap created by the limits of human information processing.

Learn more: jiminihealth.com
]]> Thu, 04 Jun 2026 13:02:00 +0000 Jimini Health Jimini Health 2826 You’ve likely heard that psychiatric progress is often stalled by subjective results. What is less understood is why the field remains slow to adopt in objective measurement even as other medical specialties thrive on hard data. Psychiatry faces a measurement gap. Dr. Arpan Parikh and Dr. Amit Parikh discusses measurement based Care, virtual health, and AI data synthesis. This is their honest account of why psychiatry must embrace measurement and how AI can finally bridge the clinical data gap. You’ve likely heard that psychiatric progress is often stalled by subjective results. What is less understood is why the field remains slow to adopt in objective measurement even as other medical specialties thrive on hard data. Psychiatry faces a measurement gap. Dr. Arpan Parikh and Dr. Amit Parikh discusses measurement based Care, virtual health, and AI data synthesis. This is their honest account of why psychiatry must embrace measurement and how AI can finally bridge the clinical data gap. Psychiatry, Mental Health, Artificial Intelligence, Measurement Based Care, Virtual Care, Telepsychiatry, Behavioral Health, Healthcare Innovation, Medicaid Care, Clinical AI No No Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt https://podcasts.fame.so/e/1n2r240n Why Your Brain Functions Like a Specialized Swiss Army Knife, with Michael Platt 12 No No 219947q1 Neuroeconomics, leadership, and brain health are essential for modern performance. Professor Michael Platt from UPenn explains why digital glass creates cognitive exhaustion. You have likely heard that our modern environment is destroying our focus. The scientific reason is that our evolutionary biology clashes with the digital tools we use every day. Professor Platt joins NeuralCompass to provide an expert account of how face-to-face connection remains the most powerful tool for leadership. This is an honest look at what your brain needs to thrive in a technological world. Analyze neuroeconomics and leadership with Professor Michael Platt from UPenn on NeuralCompass by JiminiHealth. Professor Platt joins host Mark Jacobstein to discuss the intersection of anthropology, psychology, and neuroscience. The conversation explores how the human brain functions like a Swiss Army knife evolved for an ancestral world. They examine the biological cost of video calls and the critical importance of eye contact for neural synchronization.

The discussion also covers the innovation network and the reason disengaging from routine through walking meetings is vital for creativity. Professor Platt shares data from his research on Cayo Santiago showing how social bonds increase survival in the face of catastrophic stress. Finally, the guests address the loneliness epidemic and how to foster resilience in a world dominated by digital glass.

What You’ll Learn:

  • How the social brain network hoovering up data impacts team trust.
  • The reason physical activity is the top predictor for brain vitality.
  • How to balance the task network with the default mode network for innovation.
  • The impact of digital glass on adolescent mental health and global fertility.
  • How monkey research reveals the biological price of environmental trauma.
  • Why are the most effective leadership tools, like eye contact, virtually cost-free?

About the Guest:

Michael Platt is a James Riepe University Professor at UPenn with appointments in the School of Medicine, the School of Arts and Sciences, and Wharton. He is a pioneer in the field of neuroeconomics and the author of The Leader's Brain. His research explores the biological mechanisms of decision making and social interaction in both humans and nonhuman primates.

Episode Highlights

[00:06:00] The Brain as a Swiss Army Knife: Professor Michael Platt explains that the human brain is a collection of specialized tools evolved for ancient survival. These tools are often mismatched with the current technological environment, where dopamine machines reside in every pocket. Understanding this structural mismatch helps leaders recognize why modern workers face constant information overload. This evolutionary heritage is a foundation for understanding modern psychological despair.

[00:13:00] The Social Brain and Video Call Fatigue: Digital communication disrupts the natural social brain network, which relies on constant contextual data like gaze direction and pupil size. When eye contact is broken by cameras and screens, the brain must expend significant energy to read social cues. This increased computational work leads to the exhaustion many experience after a day of virtual meetings. These insights prompted host Mark Jacobstein to modify his own camera setup to improve neural synchronization.

 [00:22:51] Walking Meetings and Innovation: Physical activity is the primary factor for maintaining brain vitality and ongoing health. Walking meetings allow the brain to disengage from routine while simultaneously fostering social connection and aerobic movement. This shift in state activates the innovation network, which is otherwise suppressed by focus-heavy tasks. Leaders can use this tool to increase the likelihood of breakthrough ideas within their teams.

[00:24:26] Task Network vs Default Mode Network: Creativity is governed by a balance between the central executive network and the default mode network. The task network fires during routine activities like spreadsheets and shuts down the regions responsible for outside-the-box thinking. To generate novel ideas, individuals must explicitly step away from their desks to allow the innovation network to fire. This neurobiological understanding explains why highly creative individuals often struggle with clerical tasks.

[00:41:01] Resilience Lessons from Monkey Island: Long-term research on rhesus macaques in Puerto Rico shows how catastrophic stress can accelerate biological aging. After Hurricane Maria, monkeys without strong social ties aged the equivalent of eight human years in a single calendar year. Monkeys that prioritized prosocial behavior and friendship demonstrated a much higher probability of survival. This research indicates that social capital acts as a biological buffer against environmental trauma.

[00:33:32] The Crisis of Digital Isolation: The modern loneliness epidemic is a primary driver of plummeting global fertility rates and rising psychological despair. Because interactions are increasingly mediated by screens, people are spending less time crossing paths in the physical world. Reclaiming free-range social experimentation for children is essential for building long-term emotional resilience. The field is actively searching for systemic guardrails like phone-free schools to mitigate these challenges.

Learn more: jiminihealth.com
]]> Mon, 01 Jun 2026 13:00:00 +0000 Jimini Health Jimini Health 2978 Neuroeconomics, leadership, and brain health are essential for modern performance. Professor Michael Platt from UPenn explains why digital glass creates cognitive exhaustion. You have likely heard that our modern environment is destroying our focus. The scientific reason is that our evolutionary biology clashes with the digital tools we use every day. Professor Platt joins NeuralCompass to provide an expert account of how face-to-face connection remains the most powerful tool for leadership. This is an honest look at what your brain needs to thrive in a technological world. Neuroeconomics, leadership, and brain health are essential for modern performance. Professor Michael Platt from UPenn explains why digital glass creates cognitive exhaustion. You have likely heard that our modern environment is destroying our focus. The scientific reason is that our evolutionary biology clashes with the digital tools we use every day. Professor Platt joins NeuralCompass to provide an expert account of how face-to-face connection remains the most powerful tool for leadership. This is an honest look at what your brain needs to thrive in a technological world. No No Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron https://podcasts.fame.so/e/pnllw3pn Why Healthcare, Ever the Tech Laggard, Finally Got the AI Memo, with Jacob Effron 11 No No x0l634x0 What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences. They cover:Why healthcare has emerged as a leading AI adoption verticalLessons from Flatiron Health on real-world data and evidenceWhat makes ambient clinical documentation a true “wedge” productHow AI can empower patients—not just cliniciansWhat separates generational health tech companies from short-lived hypeLearn more: jiminihealth.com What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?

In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences.

They cover:

  • Why healthcare has emerged as a leading AI adoption vertical
  • Lessons from Flatiron Health on real-world data and evidence
  • What makes ambient clinical documentation a true “wedge” product
  • How AI can empower patients—not just clinicians
  • What separates generational health tech companies from short-lived hype

Learn more: jiminihealth.com

]]> Tue, 07 Apr 2026 13:00:00 +0000 Jimini Health Jimini Health 2235 What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences. They cover:Why healthcare has emerged as a leading AI adoption verticalLessons from Flatiron Health on real-world data and evidenceWhat makes ambient clinical documentation a true “wedge” productHow AI can empower patients—not just cliniciansWhat separates generational health tech companies from short-lived hypeLearn more: jiminihealth.com What if healthcare’s biggest AI breakthroughs aren’t about new science—but about finally fixing systems that were never built to scale?In this episode of Neural Compass, Jacob Effron, Managing Director at Redpoint Ventures, joins Jimini’s Mark Jacobstein to explore where AI is already delivering real value in healthcare—and where hype still outpaces reality. Drawing on his experience at Flatiron Health and as an investor across AI, enterprise software, and healthcare, Jacob discusses why healthcare has become one of the fastest-adopting AI verticals, how real-world data actually creates value, and why tools that reduce clinician burden can unlock entirely new patient experiences. They cover:Why healthcare has emerged as a leading AI adoption verticalLessons from Flatiron Health on real-world data and evidenceWhat makes ambient clinical documentation a true “wedge” productHow AI can empower patients—not just cliniciansWhat separates generational health tech companies from short-lived hypeLearn more: jiminihealth.com No No Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni https://podcasts.fame.so/e/x8vl62m8 Talking “Conversational Doorknobs” & Broken Science with the Funniest Man in Psychology, Adam Mastroianni 10 No No 70ypzkm1 What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals. They cover:Why great conversations rely on “doorknobs,” not just questionsHow anxiety, status, and speed shape the way we talk to each otherWhat’s broken in modern science—and why legibility can be the enemy of discoveryWhy therapy works even when we don’t fully understand howHow imagining that “things could be better” fuels both progress and dissatisfactionLearn more: jiminihealth.com What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?

In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals.

They cover:

  • Why great conversations rely on “doorknobs,” not just questions
  • How anxiety, status, and speed shape the way we talk to each other
  • What’s broken in modern science—and why legibility can be the enemy of discovery
  • Why therapy works even when we don’t fully understand how
  • How imagining that “things could be better” fuels both progress and dissatisfaction

Learn more: jiminihealth.com

]]> Wed, 18 Mar 2026 13:00:00 +0000 Jimini Health Jimini Health 2758 What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals. They cover:Why great conversations rely on “doorknobs,” not just questionsHow anxiety, status, and speed shape the way we talk to each otherWhat’s broken in modern science—and why legibility can be the enemy of discoveryWhy therapy works even when we don’t fully understand howHow imagining that “things could be better” fuels both progress and dissatisfactionLearn more: jiminihealth.com What if the hardest problems in psychology aren’t about data or statistics—but about how we talk, think, and decide what counts as truth?In this episode of Neural Compass, psychologist, writer, and internet favorite Adam Mastroianni joins Jimini’s Mark Jacobstein for a wide-ranging conversation about conversation itself. Drawing from experimental psychology, improv, and lived experience with anxiety and depression, Adam explores why good conversations feel rare, why science struggles to study the most important questions, and why mental health progress may require ideas that don’t fit into academic boxes. Along the way, he reflects on leaving academia, rethinking peer review, and what happens when you try to tell the truth instead of writing for journals. They cover:Why great conversations rely on “doorknobs,” not just questionsHow anxiety, status, and speed shape the way we talk to each otherWhat’s broken in modern science—and why legibility can be the enemy of discoveryWhy therapy works even when we don’t fully understand howHow imagining that “things could be better” fuels both progress and dissatisfactionLearn more: jiminihealth.com No No Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO https://podcasts.fame.so/e/1n2r7j5n Tech, AI, and the Future of Therapy, with Dr. Harry Ritter, Alma's CEO 9 No No 2199n231 What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability. They cover:- Why behavioral health remained tech-averse for so long—and what changed- How Alma helps thousands of independent therapists accept insurance and scale- The hidden systems failures between payers, providers, and patients- Where AI can remove administrative burden without replacing clinicians- Why mental health may be the most powerful lever for preventive careLearn more: jiminihealth.com What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?

In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability.

They cover:

- Why behavioral health remained tech-averse for so long—and what changed

- How Alma helps thousands of independent therapists accept insurance and scale

- The hidden systems failures between payers, providers, and patients

- Where AI can remove administrative burden without replacing clinicians

- Why mental health may be the most powerful lever for preventive care

Learn more: jiminihealth.com

]]> Tue, 10 Feb 2026 14:00:00 +0000 Jimini Health Jimini Health 2390 What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability. They cover:- Why behavioral health remained tech-averse for so long—and what changed- How Alma helps thousands of independent therapists accept insurance and scale- The hidden systems failures between payers, providers, and patients- Where AI can remove administrative burden without replacing clinicians- Why mental health may be the most powerful lever for preventive careLearn more: jiminihealth.com What if fixing mental healthcare isn’t about replacing clinicians—but finally giving them the systems they’ve always lacked?In this episode of Neural Compass, Dr. Harry Ritter, founder and CEO of Alma, joins Jimini’s Mark Jacobstein to explore how technology, insurance alignment, and new business models can unlock better mental health care at scale. Drawing on his experience as a physician, lawyer, and former Oscar Health executive, Harry explains why behavioral health has lagged in tech adoption, how the pandemic permanently reshaped care delivery, and why empowering independent clinicians may be the fastest path to access, quality, and sustainability. They cover:- Why behavioral health remained tech-averse for so long—and what changed- How Alma helps thousands of independent therapists accept insurance and scale- The hidden systems failures between payers, providers, and patients- Where AI can remove administrative burden without replacing clinicians- Why mental health may be the most powerful lever for preventive careLearn more: jiminihealth.com No No Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis https://podcasts.fame.so/e/68r7vmjn Can Stress Rewire the Brain—Across a Lifetime? with Dr. Nikolaos Daskalakis 8 No No 805r5yj1 Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.They cover:* The “three-hit” model of stress: genetics, early life experience, and adult trauma* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story* What single-cell and multi-omic brain studies reveal about PTSD versus depression* The unresolved question of whether trauma can be biologically transmitted across generationsLearn more: jiminihealth.com Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?

In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.

They cover:

* The “three-hit” model of stress: genetics, early life experience, and adult trauma

* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story

* What single-cell and multi-omic brain studies reveal about PTSD versus depression

* The unresolved question of whether trauma can be biologically transmitted across generations

Learn more: jiminihealth.com

]]> Tue, 06 Jan 2026 14:00:00 +0000 Jimini Health Jimini Health 2510 Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.They cover:* The “three-hit” model of stress: genetics, early life experience, and adult trauma* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story* What single-cell and multi-omic brain studies reveal about PTSD versus depression* The unresolved question of whether trauma can be biologically transmitted across generationsLearn more: jiminihealth.com Why do some people emerge from trauma resilient, while others carry its effects for decades—or even generations?In this episode of Neural Compass, Harvard neuroscientist and psychiatrist Dr. Nikos Daskalakis joins Jimini’s Mark Jacobstein to unpack the biology of stress and PTSD. Drawing on decades of research spanning animal models, post-mortem human brain studies, and cutting-edge multi-omics, Dr. Daskalakis explains how genetics, early life stress, and later trauma interact to shape vulnerability, resilience, and mental health outcomes. The conversation explores how glucocorticoid signaling, immune–brain communication, and cell-type-specific transcriptional changes complicate our understanding of PTSD—and why simple, one-size-fits-all treatments continue to fall short.They cover:* The “three-hit” model of stress: genetics, early life experience, and adult trauma* Why cortisol and glucocorticoid signaling matter—but aren’t the whole story* What single-cell and multi-omic brain studies reveal about PTSD versus depression* The unresolved question of whether trauma can be biologically transmitted across generationsLearn more: jiminihealth.com No No Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich https://podcasts.fame.so/e/1833pqp8 Can DNA Data Unlock the Next Era of Medicine? with Dr. Yaniv Erlich 7 No No m0jpl4l0 What if the answers to mental health, aging, and disease have been encoded inside us all along?In this episode of Neural Compass, geneticist and entrepreneur Dr. Yaniv Erlich joins Jimini’s Mark Jacobstein to explore how data science and molecular biology are converging to reshape precision medicine. Dr. Erlich discusses everything from decoding the human genome to stabilizing RNA for next-generation therapeutics. Along the way, he reflects on why psychiatric traits are highly heritable, what twin studies really reveal, and why biotech innovation moves at a very different pace than tech.They discuss:- How next-generation sequencing revolutionized the study of information in DNA- The unexpected link between genealogy databases and personalized medicine- Why stabilizing RNA could make genetic therapies last longer and work better- The genetics behind mental health—and what we still don’t understand about itLearn more: jiminihealth.com What if the answers to mental health, aging, and disease have been encoded inside us all along?

In this episode of Neural Compass, geneticist and entrepreneur Dr. Yaniv Erlich joins Jimini’s Mark Jacobstein to explore how data science and molecular biology are converging to reshape precision medicine. Dr. Erlich discusses everything from decoding the human genome to stabilizing RNA for next-generation therapeutics. Along the way, he reflects on why psychiatric traits are highly heritable, what twin studies really reveal, and why biotech innovation moves at a very different pace than tech.

They discuss:

- How next-generation sequencing revolutionized the study of information in DNA

- The unexpected link between genealogy databases and personalized medicine

- Why stabilizing RNA could make genetic therapies last longer and work better

- The genetics behind mental health—and what we still don’t understand about it

Learn more: jiminihealth.com

]]> Tue, 16 Dec 2025 14:00:00 +0000 Jimini Health Jimini Health 3048 What if the answers to mental health, aging, and disease have been encoded inside us all along?In this episode of Neural Compass, geneticist and entrepreneur Dr. Yaniv Erlich joins Jimini’s Mark Jacobstein to explore how data science and molecular biology are converging to reshape precision medicine. Dr. Erlich discusses everything from decoding the human genome to stabilizing RNA for next-generation therapeutics. Along the way, he reflects on why psychiatric traits are highly heritable, what twin studies really reveal, and why biotech innovation moves at a very different pace than tech.They discuss:- How next-generation sequencing revolutionized the study of information in DNA- The unexpected link between genealogy databases and personalized medicine- Why stabilizing RNA could make genetic therapies last longer and work better- The genetics behind mental health—and what we still don’t understand about itLearn more: jiminihealth.com What if the answers to mental health, aging, and disease have been encoded inside us all along?In this episode of Neural Compass, geneticist and entrepreneur Dr. Yaniv Erlich joins Jimini’s Mark Jacobstein to explore how data science and molecular biology are converging to reshape precision medicine. Dr. Erlich discusses everything from decoding the human genome to stabilizing RNA for next-generation therapeutics. Along the way, he reflects on why psychiatric traits are highly heritable, what twin studies really reveal, and why biotech innovation moves at a very different pace than tech.They discuss:- How next-generation sequencing revolutionized the study of information in DNA- The unexpected link between genealogy databases and personalized medicine- Why stabilizing RNA could make genetic therapies last longer and work better- The genetics behind mental health—and what we still don’t understand about itLearn more: jiminihealth.com No No Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky https://podcasts.fame.so/e/286qvmjn Is this the "Century of the Brain"? with Greg Kubin & Matias Serebrinsky 6 No No j12r3741 What if the next breakthrough in mental health isn’t a molecule—but a mindset?In this episode of Neural Compass, PsyMed Ventures co-founders Greg Kubin and Matias Serebrinsky join Jimini’s Mark Jacobstein to trace their journey from tech founders to frontier investors betting on the brain. They share how personal experiences with therapy and psychedelics reshaped their view of healing, and why the future of mental health may depend on tools that don’t just treat illness—but expand human potential.They cover:- How psychedelics opened the door to a new kind of neuroscience investing- Why the “century of the brain” will blur the lines between treatment and enhancement- The business and ethical challenges of funding radical innovation- What flourishing—not just recovery—could look like in the decades aheadLearn more: jiminihealth.com What if the next breakthrough in mental health isn’t a molecule—but a mindset?

In this episode of Neural Compass, PsyMed Ventures co-founders Greg Kubin and Matias Serebrinsky join Jimini’s Mark Jacobstein to trace their journey from tech founders to frontier investors betting on the brain. They share how personal experiences with therapy and psychedelics reshaped their view of healing, and why the future of mental health may depend on tools that don’t just treat illness—but expand human potential.

They cover:

- How psychedelics opened the door to a new kind of neuroscience investing

- Why the “century of the brain” will blur the lines between treatment and enhancement

- The business and ethical challenges of funding radical innovation

- What flourishing—not just recovery—could look like in the decades ahead

Learn more: jiminihealth.com

]]> Tue, 25 Nov 2025 14:00:00 +0000 Jimini Health Jimini Health 2629 What if the next breakthrough in mental health isn’t a molecule—but a mindset?In this episode of Neural Compass, PsyMed Ventures co-founders Greg Kubin and Matias Serebrinsky join Jimini’s Mark Jacobstein to trace their journey from tech founders to frontier investors betting on the brain. They share how personal experiences with therapy and psychedelics reshaped their view of healing, and why the future of mental health may depend on tools that don’t just treat illness—but expand human potential.They cover:- How psychedelics opened the door to a new kind of neuroscience investing- Why the “century of the brain” will blur the lines between treatment and enhancement- The business and ethical challenges of funding radical innovation- What flourishing—not just recovery—could look like in the decades aheadLearn more: jiminihealth.com What if the next breakthrough in mental health isn’t a molecule—but a mindset?In this episode of Neural Compass, PsyMed Ventures co-founders Greg Kubin and Matias Serebrinsky join Jimini’s Mark Jacobstein to trace their journey from tech founders to frontier investors betting on the brain. They share how personal experiences with therapy and psychedelics reshaped their view of healing, and why the future of mental health may depend on tools that don’t just treat illness—but expand human potential.They cover:- How psychedelics opened the door to a new kind of neuroscience investing- Why the “century of the brain” will blur the lines between treatment and enhancement- The business and ethical challenges of funding radical innovation- What flourishing—not just recovery—could look like in the decades aheadLearn more: jiminihealth.com No No Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber https://podcasts.fame.so/e/0njy5228 Are We Teaching AI to Care—or Just to Sound Like It? with Dr. Nick Haber 5 No No 40pq9441 What happens when the tools we build to understand us start to change what it means to be human?In this episode of Neural Compass, Stanford’s Dr. Nick Haber—computer scientist, educator, and co-founder of the Autism Glass Project—joins Jimini’s Mark Jacobstein to explore how AI is entering some of the most human spaces: learning, emotion, and mental health.From wearable devices that help children with autism recognize emotion to new research on large language models in therapy, Dr. Haber examines both the promise and the peril of AI that seems to “care.”They cover:- How wearable AI helped children with autism connect through emotion recognition- Why today’s chatbots still miss critical signs of distress—and what that reveals about human empathy- How AI might train, not replace, the next generation of therapists- Why the line between assistive and autonomous AI may define the future of careLearn more: jiminihealth.com What happens when the tools we build to understand us start to change what it means to be human?

In this episode of Neural Compass, Stanford’s Dr. Nick Haber—computer scientist, educator, and co-founder of the Autism Glass Project—joins Jimini’s Mark Jacobstein to explore how AI is entering some of the most human spaces: learning, emotion, and mental health.

From wearable devices that help children with autism recognize emotion to new research on large language models in therapy, Dr. Haber examines both the promise and the peril of AI that seems to “care.”

They cover:

- How wearable AI helped children with autism connect through emotion recognition

- Why today’s chatbots still miss critical signs of distress—and what that reveals about human empathy

- How AI might train, not replace, the next generation of therapists

- Why the line between assistive and autonomous AI may define the future of care

Learn more: jiminihealth.com

]]> Tue, 11 Nov 2025 14:00:00 +0000 Jimini Health Jimini Health 2549 What happens when the tools we build to understand us start to change what it means to be human?In this episode of Neural Compass, Stanford’s Dr. Nick Haber—computer scientist, educator, and co-founder of the Autism Glass Project—joins Jimini’s Mark Jacobstein to explore how AI is entering some of the most human spaces: learning, emotion, and mental health.From wearable devices that help children with autism recognize emotion to new research on large language models in therapy, Dr. Haber examines both the promise and the peril of AI that seems to “care.”They cover:- How wearable AI helped children with autism connect through emotion recognition- Why today’s chatbots still miss critical signs of distress—and what that reveals about human empathy- How AI might train, not replace, the next generation of therapists- Why the line between assistive and autonomous AI may define the future of careLearn more: jiminihealth.com What happens when the tools we build to understand us start to change what it means to be human?In this episode of Neural Compass, Stanford’s Dr. Nick Haber—computer scientist, educator, and co-founder of the Autism Glass Project—joins Jimini’s Mark Jacobstein to explore how AI is entering some of the most human spaces: learning, emotion, and mental health.From wearable devices that help children with autism recognize emotion to new research on large language models in therapy, Dr. Haber examines both the promise and the peril of AI that seems to “care.”They cover:- How wearable AI helped children with autism connect through emotion recognition- Why today’s chatbots still miss critical signs of distress—and what that reveals about human empathy- How AI might train, not replace, the next generation of therapists- Why the line between assistive and autonomous AI may define the future of careLearn more: jiminihealth.com No No What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko https://podcasts.fame.so/e/lnqw50kn What Does It Take To Reform Mental Health Care From The Inside Out? with Mike Kopko 4 No No 81nv3471 In this episode of Neural Compass, Mike Kopko—CEO and co-founder of Pearl Health—joins Jimini’s Mark Jacobstein to explore how value-based care, provider enablement, and intelligent incentives could finally help us build the system we deserve.They cover:- Why physicians—not hospitals or payers—are the key to real health care transformation- How value-based care forces a shift from rear-view to windshield thinking- What makes primary care the most underleveraged force in the system- Why mental health interventions struggle for investment—and how to change that- The real promise of AI: getting the right care to the right person, at the right timeLearn more: jiminihealth.com In this episode of Neural Compass, Mike Kopko—CEO and co-founder of Pearl Health—joins Jimini’s Mark Jacobstein to explore how value-based care, provider enablement, and intelligent incentives could finally help us build the system we deserve.

They cover:

- Why physicians—not hospitals or payers—are the key to real health care transformation

- How value-based care forces a shift from rear-view to windshield thinking

- What makes primary care the most underleveraged force in the system

- Why mental health interventions struggle for investment—and how to change that

- The real promise of AI: getting the right care to the right person, at the right time

Learn more: jiminihealth.com

]]> Tue, 04 Nov 2025 14:00:00 +0000 Jimini Health Jimini Health 2369 In this episode of Neural Compass, Mike Kopko—CEO and co-founder of Pearl Health—joins Jimini’s Mark Jacobstein to explore how value-based care, provider enablement, and intelligent incentives could finally help us build the system we deserve.They cover:- Why physicians—not hospitals or payers—are the key to real health care transformation- How value-based care forces a shift from rear-view to windshield thinking- What makes primary care the most underleveraged force in the system- Why mental health interventions struggle for investment—and how to change that- The real promise of AI: getting the right care to the right person, at the right timeLearn more: jiminihealth.com In this episode of Neural Compass, Mike Kopko—CEO and co-founder of Pearl Health—joins Jimini’s Mark Jacobstein to explore how value-based care, provider enablement, and intelligent incentives could finally help us build the system we deserve.They cover:- Why physicians—not hospitals or payers—are the key to real health care transformation- How value-based care forces a shift from rear-view to windshield thinking- What makes primary care the most underleveraged force in the system- Why mental health interventions struggle for investment—and how to change that- The real promise of AI: getting the right care to the right person, at the right timeLearn more: jiminihealth.com No No Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal https://podcasts.fame.so/e/mn4l74xn Could Ketamine Unlock a New Era in Mental Health? with Dr. John Krystal 3 No No x06rj9l0 What happens when decades of groundbreaking neuroscience challenge everything we thought we knew about depression?In this episode of Neural Compass, Dr. John Krystal—Chair of Psychiatry at Yale and the scientist whose lab discovered the rapid antidepressant effects of ketamine—joins Jimini’s Mark Jacobstein to explore how novel treatments are reshaping the future of mental health.They cover:- The story behind ketamine’s unexpected antidepressant effects- Why depression may be rooted in the cortex—not just monoamines- How synaptic regrowth fuels resilience and recovery- The promise and perils of psychedelics as clinical therapiesLearn more: jiminihealth.com What happens when decades of groundbreaking neuroscience challenge everything we thought we knew about depression?

In this episode of Neural Compass, Dr. John Krystal—Chair of Psychiatry at Yale and the scientist whose lab discovered the rapid antidepressant effects of ketamine—joins Jimini’s Mark Jacobstein to explore how novel treatments are reshaping the future of mental health.

They cover:

- The story behind ketamine’s unexpected antidepressant effects

- Why depression may be rooted in the cortex—not just monoamines

- How synaptic regrowth fuels resilience and recovery

- The promise and perils of psychedelics as clinical therapies

Learn more: jiminihealth.com

]]> Tue, 28 Oct 2025 13:00:00 +0000 Jimini Health Jimini Health 2570 What happens when decades of groundbreaking neuroscience challenge everything we thought we knew about depression?In this episode of Neural Compass, Dr. John Krystal—Chair of Psychiatry at Yale and the scientist whose lab discovered the rapid antidepressant effects of ketamine—joins Jimini’s Mark Jacobstein to explore how novel treatments are reshaping the future of mental health.They cover:- The story behind ketamine’s unexpected antidepressant effects- Why depression may be rooted in the cortex—not just monoamines- How synaptic regrowth fuels resilience and recovery- The promise and perils of psychedelics as clinical therapiesLearn more: jiminihealth.com What happens when decades of groundbreaking neuroscience challenge everything we thought we knew about depression?In this episode of Neural Compass, Dr. John Krystal—Chair of Psychiatry at Yale and the scientist whose lab discovered the rapid antidepressant effects of ketamine—joins Jimini’s Mark Jacobstein to explore how novel treatments are reshaping the future of mental health.They cover:- The story behind ketamine’s unexpected antidepressant effects- Why depression may be rooted in the cortex—not just monoamines- How synaptic regrowth fuels resilience and recovery- The promise and perils of psychedelics as clinical therapiesLearn more: jiminihealth.com No No How Do We Deliver Better Mental Health Care At Scale? with Dr. Stephanie Eken https://podcasts.fame.so/e/q80vz3v8 How Do We Deliver Better Mental Health Care At Scale? with Dr. Stephanie Eken 2 No No p0kn34n1 What does it actually take to deliver high-quality behavioral health care to hundreds of thousands of people?In this episode of Neural Compass, Dr. Stephanie Eken—Chief Medical Officer at Acadia Healthcare—joins Jimini’s Mark Jacobstein to talk about what works (and what still doesn’t) in the real-world mental health system.They cover:- Why navigating care is still so hard—for patients, families, and even physicians- The surprising promise of AI and ambient tech in closing the fidelity gap- What schools, churches, and state fairs have to do with early intervention- Why loneliness, stigma, and gender norms still shape how (and if) people get careLearn more: jiminihealth.com What does it actually take to deliver high-quality behavioral health care to hundreds of thousands of people?

In this episode of Neural Compass, Dr. Stephanie Eken—Chief Medical Officer at Acadia Healthcare—joins Jimini’s Mark Jacobstein to talk about what works (and what still doesn’t) in the real-world mental health system.

They cover:

- Why navigating care is still so hard—for patients, families, and even physicians

- The surprising promise of AI and ambient tech in closing the fidelity gap

- What schools, churches, and state fairs have to do with early intervention

- Why loneliness, stigma, and gender norms still shape how (and if) people get care

Learn more: jiminihealth.com

]]> Wed, 22 Oct 2025 13:00:00 +0000 Jimini Health Jimini Health 2539 What does it actually take to deliver high-quality behavioral health care to hundreds of thousands of people?In this episode of Neural Compass, Dr. Stephanie Eken—Chief Medical Officer at Acadia Healthcare—joins Jimini’s Mark Jacobstein to talk about what works (and what still doesn’t) in the real-world mental health system.They cover:- Why navigating care is still so hard—for patients, families, and even physicians- The surprising promise of AI and ambient tech in closing the fidelity gap- What schools, churches, and state fairs have to do with early intervention- Why loneliness, stigma, and gender norms still shape how (and if) people get careLearn more: jiminihealth.com What does it actually take to deliver high-quality behavioral health care to hundreds of thousands of people?In this episode of Neural Compass, Dr. Stephanie Eken—Chief Medical Officer at Acadia Healthcare—joins Jimini’s Mark Jacobstein to talk about what works (and what still doesn’t) in the real-world mental health system.They cover:- Why navigating care is still so hard—for patients, families, and even physicians- The surprising promise of AI and ambient tech in closing the fidelity gap- What schools, churches, and state fairs have to do with early intervention- Why loneliness, stigma, and gender norms still shape how (and if) people get careLearn more: jiminihealth.com No No Is the Brain More Flexible Than We Ever Imagined? with David Eagleman https://podcasts.fame.so/e/p8m7k628 Is the Brain More Flexible Than We Ever Imagined? with David Eagleman 1 No No 70v56px1 In this episode of Neural Compass, David Eagleman—Stanford neuroscientist, bestselling author of Livewired, and one of today’s leading communicators of brain science—joins Jimini’s Mark Jacobstein to explore the astonishing adaptability of the human brain and its implications for therapy, technology, and society.They cover:- Why Eagleman calls the brain livewired—not “plastic”—and how it constantly reshapes itself- How neuroplasticity is central to everything from therapy to psychedelics to brain stimulation- The promise of sensory substitution—from helping deaf individuals “hear” through vibrations to new frontiers in brain–computer interfaces- The legal and ethical questions raised when brain science meets crime, culpability, and justice- The future of human–AI interaction—from companion robots to algorithms that could reduce polarization instead of fueling itLearn more: jiminihealth.com In this episode of Neural Compass, David Eagleman—Stanford neuroscientist, bestselling author of Livewired, and one of today’s leading communicators of brain science—joins Jimini’s Mark Jacobstein to explore the astonishing adaptability of the human brain and its implications for therapy, technology, and society.

They cover:

- Why Eagleman calls the brain livewired—not “plastic”—and how it constantly reshapes itself

- How neuroplasticity is central to everything from therapy to psychedelics to brain stimulation

- The promise of sensory substitution—from helping deaf individuals “hear” through vibrations to new frontiers in brain–computer interfaces

- The legal and ethical questions raised when brain science meets crime, culpability, and justice

- The future of human–AI interaction—from companion robots to algorithms that could reduce polarization instead of fueling it

Learn more: jiminihealth.com

]]> Thu, 16 Oct 2025 13:00:00 +0000 Jimini Health Jimini Health 2474 In this episode of Neural Compass, David Eagleman—Stanford neuroscientist, bestselling author of Livewired, and one of today’s leading communicators of brain science—joins Jimini’s Mark Jacobstein to explore the astonishing adaptability of the human brain and its implications for therapy, technology, and society.They cover:- Why Eagleman calls the brain livewired—not “plastic”—and how it constantly reshapes itself- How neuroplasticity is central to everything from therapy to psychedelics to brain stimulation- The promise of sensory substitution—from helping deaf individuals “hear” through vibrations to new frontiers in brain–computer interfaces- The legal and ethical questions raised when brain science meets crime, culpability, and justice- The future of human–AI interaction—from companion robots to algorithms that could reduce polarization instead of fueling itLearn more: jiminihealth.com In this episode of Neural Compass, David Eagleman—Stanford neuroscientist, bestselling author of Livewired, and one of today’s leading communicators of brain science—joins Jimini’s Mark Jacobstein to explore the astonishing adaptability of the human brain and its implications for therapy, technology, and society.They cover:- Why Eagleman calls the brain livewired—not “plastic”—and how it constantly reshapes itself- How neuroplasticity is central to everything from therapy to psychedelics to brain stimulation- The promise of sensory substitution—from helping deaf individuals “hear” through vibrations to new frontiers in brain–computer interfaces- The legal and ethical questions raised when brain science meets crime, culpability, and justice- The future of human–AI interaction—from companion robots to algorithms that could reduce polarization instead of fueling itLearn more: jiminihealth.com No No How can we design mental health tools people actually use and trust? with Stephen Duke https://podcasts.fame.so/e/28xzq3l8 How can we design mental health tools people actually use and trust? with Stephen Duke 11 No No 60mk34y0 What happens when a McKinsey alum with a personal history of OCD turns his analytical superpowers toward fixing mental health care?In this episode of Neural Compass, Steve Duke—founder of the Hemingway Group and author of the must-read Hemingway Report—joins Jimini’s Mark Jacobstein for a compelling conversation on the present (and future) of behavioral health.They cover:
- Why the mental health system rewards what’s reimbursable—not necessarily what works
- How AI is already being used for emotional support—and what we aren’t talking about enough
- The trust paradox of conversational agents in mental health
- How loneliness, sleep, and social connection are massively underleveraged interventions
- What the rise of run clubs and cold plunges might teach us about health tech adoptionLearn more: jiminihealth.com What happens when a McKinsey alum with a personal history of OCD turns his analytical superpowers toward fixing mental health care?

In this episode of Neural Compass, Steve Duke—founder of the Hemingway Group and author of the must-read Hemingway Report—joins Jimini’s Mark Jacobstein for a compelling conversation on the present (and future) of behavioral health.

They cover:


- Why the mental health system rewards what’s reimbursable—not necessarily what works


- How AI is already being used for emotional support—and what we aren’t talking about enough


- The trust paradox of conversational agents in mental health


- How loneliness, sleep, and social connection are massively underleveraged interventions


- What the rise of run clubs and cold plunges might teach us about health tech adoption

Learn more: jiminihealth.com

]]> Tue, 29 Jul 2025 13:00:00 +0000 Jimini Health Jimini Health 2853 What happens when a McKinsey alum with a personal history of OCD turns his analytical superpowers toward fixing mental health care?In this episode of Neural Compass, Steve Duke—founder of the Hemingway Group and author of the must-read Hemingway Report—joins Jimini’s Mark Jacobstein for a compelling conversation on the present (and future) of behavioral health.They cover:
- Why the mental health system rewards what’s reimbursable—not necessarily what works
- How AI is already being used for emotional support—and what we aren’t talking about enough
- The trust paradox of conversational agents in mental health
- How loneliness, sleep, and social connection are massively underleveraged interventions
- What the rise of run clubs and cold plunges might teach us about health tech adoptionLearn more: jiminihealth.com What happens when a McKinsey alum with a personal history of OCD turns his analytical superpowers toward fixing mental health care?In this episode of Neural Compass, Steve Duke—founder of the Hemingway Group and author of the must-read Hemingway Report—joins Jimini’s Mark Jacobstein for a compelling conversation on the present (and future) of behavioral health.They cover:
- Why the mental health system rewards what’s reimbursable—not necessarily what works
- How AI is already being used for emotional support—and what we aren’t talking about enough
- The trust paradox of conversational agents in mental health
- How loneliness, sleep, and social connection are massively underleveraged interventions
- What the rise of run clubs and cold plunges might teach us about health tech adoptionLearn more: jiminihealth.com No No What If AI Could Help Us Save Lives? with Dr. Seth Feuerstein https://podcasts.fame.so/e/v85j703n What If AI Could Help Us Save Lives? with Dr. Seth Feuerstein 10 No No 81q35ym1 In this episode of Neural Compass, Dr. Seth Feuerstein, Founder & CEO of Oui Therapeutics and Yale faculty member, joins Jimini’s Mark Jacobstein for a compelling conversation on why our mental health system overlooks what the data actually says—and what we can do about it.They cover:- A surprising model that redefines how we understand suicidality- Why talk therapy often works—but also often fails- What it takes to bring real innovation into clinical care- The hidden mental toll of constant digital bombardmentLearn more: jiminihealth.com In this episode of Neural Compass, Dr. Seth Feuerstein, Founder & CEO of Oui Therapeutics and Yale faculty member, joins Jimini’s Mark Jacobstein for a compelling conversation on why our mental health system overlooks what the data actually says—and what we can do about it.

They cover:

- A surprising model that redefines how we understand suicidality

- Why talk therapy often works—but also often fails

- What it takes to bring real innovation into clinical care

- The hidden mental toll of constant digital bombardment

Learn more: jiminihealth.com

]]> Tue, 22 Jul 2025 13:00:00 +0000 Jimini Health Jimini Health 2856 In this episode of Neural Compass, Dr. Seth Feuerstein, Founder & CEO of Oui Therapeutics and Yale faculty member, joins Jimini’s Mark Jacobstein for a compelling conversation on why our mental health system overlooks what the data actually says—and what we can do about it.They cover:- A surprising model that redefines how we understand suicidality- Why talk therapy often works—but also often fails- What it takes to bring real innovation into clinical care- The hidden mental toll of constant digital bombardmentLearn more: jiminihealth.com In this episode of Neural Compass, Dr. Seth Feuerstein, Founder & CEO of Oui Therapeutics and Yale faculty member, joins Jimini’s Mark Jacobstein for a compelling conversation on why our mental health system overlooks what the data actually says—and what we can do about it.They cover:- A surprising model that redefines how we understand suicidality- Why talk therapy often works—but also often fails- What it takes to bring real innovation into clinical care- The hidden mental toll of constant digital bombardmentLearn more: jiminihealth.com No No How Do We Put Guardrails on AI? with Shreya Rajpal https://podcasts.fame.so/e/xn1276m8 How Do We Put Guardrails on AI? with Shreya Rajpal 9 No No 703ry7k1 What do you get when a leading AI safety innovator, systems thinker, and open-source champion sits down to talk product, philosophy, and the future of LLMs? A conversation that redefines what it means to build responsibly in the age of generative AI.In this episode of Neural Compass, Shreya Rajpal—CEO of Guardrails AI and former self-driving systems engineer—joins Jimini’s Mark Jacobstein to explore the deep tech and deeper questions behind safe, scalable, and human-aligned AI.They cover:- What self-driving cars can teach us about LLM reliability- Why “accuracy” isn’t the right metric anymore- How simulation testing might be the key to safety at scale- The puzzle-solving mindset that drives both engineering and leadershipLearn more: jiminihealth.com What do you get when a leading AI safety innovator, systems thinker, and open-source champion sits down to talk product, philosophy, and the future of LLMs? A conversation that redefines what it means to build responsibly in the age of generative AI.

In this episode of Neural Compass, Shreya Rajpal—CEO of Guardrails AI and former self-driving systems engineer—joins Jimini’s Mark Jacobstein to explore the deep tech and deeper questions behind safe, scalable, and human-aligned AI.

They cover:

- What self-driving cars can teach us about LLM reliability

- Why “accuracy” isn’t the right metric anymore

- How simulation testing might be the key to safety at scale

- The puzzle-solving mindset that drives both engineering and leadership

Learn more: jiminihealth.com

]]> Tue, 15 Jul 2025 13:00:00 +0000 Jimini Health Jimini Health 2384 What do you get when a leading AI safety innovator, systems thinker, and open-source champion sits down to talk product, philosophy, and the future of LLMs? A conversation that redefines what it means to build responsibly in the age of generative AI.In this episode of Neural Compass, Shreya Rajpal—CEO of Guardrails AI and former self-driving systems engineer—joins Jimini’s Mark Jacobstein to explore the deep tech and deeper questions behind safe, scalable, and human-aligned AI.They cover:- What self-driving cars can teach us about LLM reliability- Why “accuracy” isn’t the right metric anymore- How simulation testing might be the key to safety at scale- The puzzle-solving mindset that drives both engineering and leadershipLearn more: jiminihealth.com What do you get when a leading AI safety innovator, systems thinker, and open-source champion sits down to talk product, philosophy, and the future of LLMs? A conversation that redefines what it means to build responsibly in the age of generative AI.In this episode of Neural Compass, Shreya Rajpal—CEO of Guardrails AI and former self-driving systems engineer—joins Jimini’s Mark Jacobstein to explore the deep tech and deeper questions behind safe, scalable, and human-aligned AI.They cover:- What self-driving cars can teach us about LLM reliability- Why “accuracy” isn’t the right metric anymore- How simulation testing might be the key to safety at scale- The puzzle-solving mindset that drives both engineering and leadershipLearn more: jiminihealth.com No No What if "Crushing It" is Crushing You? with Jerry Colonna https://podcasts.fame.so/e/x8y746r8 What if "Crushing It" is Crushing You? with Jerry Colonna 8 No No l04r9720 What happens when a legendary VC-turned-leadership coach brings radical self-inquiry to the startup roller coaster? A conversation that rewrites what it means to lead—with grit, honesty, and a whole lot of heart.In this episode of Neural Compass, Jerry Colonna—CEO of Reboot.io and author of Reboot and Reunion—joins Jimini’s Mark Jacobstein for a powerful reflection on mental health, emotional resilience, and the inner lives of leaders.They cover:- Why “false grit” is hurting founders more than it’s helping- How to detach your self-worth from your startup’s performance- The ghosts in the machine—and how to face them- Why leadership starts with healingLearn more: jiminihealth.com What happens when a legendary VC-turned-leadership coach brings radical self-inquiry to the startup roller coaster? A conversation that rewrites what it means to lead—with grit, honesty, and a whole lot of heart.

In this episode of Neural Compass, Jerry Colonna—CEO of Reboot.io and author of Reboot and Reunion—joins Jimini’s Mark Jacobstein for a powerful reflection on mental health, emotional resilience, and the inner lives of leaders.

They cover:

- Why “false grit” is hurting founders more than it’s helping

- How to detach your self-worth from your startup’s performance

- The ghosts in the machine—and how to face them

- Why leadership starts with healing

Learn more: jiminihealth.com

]]> Tue, 08 Jul 2025 13:00:00 +0000 Jimini Health Jimini Health 1412 What happens when a legendary VC-turned-leadership coach brings radical self-inquiry to the startup roller coaster? A conversation that rewrites what it means to lead—with grit, honesty, and a whole lot of heart.In this episode of Neural Compass, Jerry Colonna—CEO of Reboot.io and author of Reboot and Reunion—joins Jimini’s Mark Jacobstein for a powerful reflection on mental health, emotional resilience, and the inner lives of leaders.They cover:- Why “false grit” is hurting founders more than it’s helping- How to detach your self-worth from your startup’s performance- The ghosts in the machine—and how to face them- Why leadership starts with healingLearn more: jiminihealth.com What happens when a legendary VC-turned-leadership coach brings radical self-inquiry to the startup roller coaster? A conversation that rewrites what it means to lead—with grit, honesty, and a whole lot of heart.In this episode of Neural Compass, Jerry Colonna—CEO of Reboot.io and author of Reboot and Reunion—joins Jimini’s Mark Jacobstein for a powerful reflection on mental health, emotional resilience, and the inner lives of leaders.They cover:- Why “false grit” is hurting founders more than it’s helping- How to detach your self-worth from your startup’s performance- The ghosts in the machine—and how to face them- Why leadership starts with healingLearn more: jiminihealth.com No No How is Machine Learning Improving the How, What, and When of Cancer Diagnosis? with Dr. Adam Yala https://podcasts.fame.so/e/rnkl50j8 How is Machine Learning Improving the How, What, and When of Cancer Diagnosis? with Dr. Adam Yala 7 No No 70wjkp91 What happens when a precision health researcher reimagines cancer screening from the ground up—and then builds the AI to make it possible?In this episode of Neural Compass, Dr. Adam Yala, Assistant Professor at UC Berkeley and UCSF, joins Jimini’s Mark Jacobstein for a deep dive into the future of personalized medicine.They cover:- Why traditional cancer screening is too coarse—and how AI can change that- Building risk prediction models that outperform today’s gold standards- The challenges (and promise) of applying machine learning in real clinical workflows- What adaptive trials, synthetic data, and LLM safety have in commonLearn more: jiminihealth.com What happens when a precision health researcher reimagines cancer screening from the ground up—and then builds the AI to make it possible?

In this episode of Neural Compass, Dr. Adam Yala, Assistant Professor at UC Berkeley and UCSF, joins Jimini’s Mark Jacobstein for a deep dive into the future of personalized medicine.

They cover:

- Why traditional cancer screening is too coarse—and how AI can change that

- Building risk prediction models that outperform today’s gold standards

- The challenges (and promise) of applying machine learning in real clinical workflows

- What adaptive trials, synthetic data, and LLM safety have in common

Learn more: jiminihealth.com

]]> Tue, 01 Jul 2025 14:20:00 +0000 Jimini Health Jimini Health 2387 What happens when a precision health researcher reimagines cancer screening from the ground up—and then builds the AI to make it possible?In this episode of Neural Compass, Dr. Adam Yala, Assistant Professor at UC Berkeley and UCSF, joins Jimini’s Mark Jacobstein for a deep dive into the future of personalized medicine.They cover:- Why traditional cancer screening is too coarse—and how AI can change that- Building risk prediction models that outperform today’s gold standards- The challenges (and promise) of applying machine learning in real clinical workflows- What adaptive trials, synthetic data, and LLM safety have in commonLearn more: jiminihealth.com What happens when a precision health researcher reimagines cancer screening from the ground up—and then builds the AI to make it possible?In this episode of Neural Compass, Dr. Adam Yala, Assistant Professor at UC Berkeley and UCSF, joins Jimini’s Mark Jacobstein for a deep dive into the future of personalized medicine.They cover:- Why traditional cancer screening is too coarse—and how AI can change that- Building risk prediction models that outperform today’s gold standards- The challenges (and promise) of applying machine learning in real clinical workflows- What adaptive trials, synthetic data, and LLM safety have in commonLearn more: jiminihealth.com No No What Happens When You Believe In AI Before Everyone Else? with Yan-David “Yanda” Erlich https://podcasts.fame.so/e/489m3xq8 What Happens When You Believe In AI Before Everyone Else? with Yan-David “Yanda” Erlich 6 No No v17r2z70 What if building great AI isn’t just about data and models—but about the mindset of the people behind it?In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Yanda Erlich, a four-time founder, longtime AI investor, and general partner at B Capital. They explore what it means to bet on AI before it’s obvious—and how inner work can shape better leaders, companies, and decisions along the way.Yanda shares the story of investing early in Weights & Biases, lessons from launching one of the first agentic AI startups, and the mental frameworks he uses daily to navigate uncertainty. It’s a rare blend of venture insight and emotional intelligence—rooted in meditation, inquiry, and a belief that the future of AI starts with the people building it.They cover:- Why timing and conviction matter more than being first in AI- The connection between inner work and good decision-making- How to run inquiry-based mental health practices (yes, even 200 times a day)- What early AI founders got right—and wrong—before the LLM era- Reframing emotional struggles as opportunities for learning and insightLearn more: jiminihealth.com What if building great AI isn’t just about data and models—but about the mindset of the people behind it?

In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Yanda Erlich, a four-time founder, longtime AI investor, and general partner at B Capital. They explore what it means to bet on AI before it’s obvious—and how inner work can shape better leaders, companies, and decisions along the way.

Yanda shares the story of investing early in Weights & Biases, lessons from launching one of the first agentic AI startups, and the mental frameworks he uses daily to navigate uncertainty. It’s a rare blend of venture insight and emotional intelligence—rooted in meditation, inquiry, and a belief that the future of AI starts with the people building it.

They cover:

- Why timing and conviction matter more than being first in AI

- The connection between inner work and good decision-making

- How to run inquiry-based mental health practices (yes, even 200 times a day)

- What early AI founders got right—and wrong—before the LLM era

- Reframing emotional struggles as opportunities for learning and insight

Learn more: jiminihealth.com

]]> Tue, 24 Jun 2025 13:00:00 +0000 Jimini Health Jimini Health 2727 What if building great AI isn’t just about data and models—but about the mindset of the people behind it?In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Yanda Erlich, a four-time founder, longtime AI investor, and general partner at B Capital. They explore what it means to bet on AI before it’s obvious—and how inner work can shape better leaders, companies, and decisions along the way.Yanda shares the story of investing early in Weights & Biases, lessons from launching one of the first agentic AI startups, and the mental frameworks he uses daily to navigate uncertainty. It’s a rare blend of venture insight and emotional intelligence—rooted in meditation, inquiry, and a belief that the future of AI starts with the people building it.They cover:- Why timing and conviction matter more than being first in AI- The connection between inner work and good decision-making- How to run inquiry-based mental health practices (yes, even 200 times a day)- What early AI founders got right—and wrong—before the LLM era- Reframing emotional struggles as opportunities for learning and insightLearn more: jiminihealth.com What if building great AI isn’t just about data and models—but about the mindset of the people behind it?In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Yanda Erlich, a four-time founder, longtime AI investor, and general partner at B Capital. They explore what it means to bet on AI before it’s obvious—and how inner work can shape better leaders, companies, and decisions along the way.Yanda shares the story of investing early in Weights & Biases, lessons from launching one of the first agentic AI startups, and the mental frameworks he uses daily to navigate uncertainty. It’s a rare blend of venture insight and emotional intelligence—rooted in meditation, inquiry, and a belief that the future of AI starts with the people building it.They cover:- Why timing and conviction matter more than being first in AI- The connection between inner work and good decision-making- How to run inquiry-based mental health practices (yes, even 200 times a day)- What early AI founders got right—and wrong—before the LLM era- Reframing emotional struggles as opportunities for learning and insightLearn more: jiminihealth.com No No Why Can’t Mental Health Innovations Reach the People Who Need Them Most? with Dr. Amber Childs https://podcasts.fame.so/e/x8vl6zy8 Why Can’t Mental Health Innovations Reach the People Who Need Them Most? with Dr. Amber Childs 5 No No 70ypz641 What if the data you collect could actually make mental health care more human?Dr. Amber Childs, Yale psychologist and expert in adolescent mental health, says measurement-based care isn’t just about numbers—it’s about connection. When done right, it strengthens the therapeutic alliance, empowers patients, and helps clinicians catch what they might otherwise miss.In episode five of Neural Compass, Dr. Childs shares how we can use data to close equity gaps, personalize treatment, and design systems that actually serve the people in them.They cover:- What measurement-based care really looks like in practice- How Dr. Childs built a tool to reduce clinician burnout and improve outcomes- Why the future of behavioral health must include caregiver voices- The entrepreneurial lessons she learned turning a “flip-flop budget” into system-wide changeLearn more: jiminihealth.com What if the data you collect could actually make mental health care more human?

Dr. Amber Childs, Yale psychologist and expert in adolescent mental health, says measurement-based care isn’t just about numbers—it’s about connection. When done right, it strengthens the therapeutic alliance, empowers patients, and helps clinicians catch what they might otherwise miss.

In episode five of Neural Compass, Dr. Childs shares how we can use data to close equity gaps, personalize treatment, and design systems that actually serve the people in them.

They cover:

- What measurement-based care really looks like in practice

- How Dr. Childs built a tool to reduce clinician burnout and improve outcomes

- Why the future of behavioral health must include caregiver voices

- The entrepreneurial lessons she learned turning a “flip-flop budget” into system-wide change

Learn more: jiminihealth.com

]]> Tue, 17 Jun 2025 13:01:00 +0000 Jimini Health Jimini Health 2859 What if the data you collect could actually make mental health care more human?Dr. Amber Childs, Yale psychologist and expert in adolescent mental health, says measurement-based care isn’t just about numbers—it’s about connection. When done right, it strengthens the therapeutic alliance, empowers patients, and helps clinicians catch what they might otherwise miss.In episode five of Neural Compass, Dr. Childs shares how we can use data to close equity gaps, personalize treatment, and design systems that actually serve the people in them.They cover:- What measurement-based care really looks like in practice- How Dr. Childs built a tool to reduce clinician burnout and improve outcomes- Why the future of behavioral health must include caregiver voices- The entrepreneurial lessons she learned turning a “flip-flop budget” into system-wide changeLearn more: jiminihealth.com What if the data you collect could actually make mental health care more human?Dr. Amber Childs, Yale psychologist and expert in adolescent mental health, says measurement-based care isn’t just about numbers—it’s about connection. When done right, it strengthens the therapeutic alliance, empowers patients, and helps clinicians catch what they might otherwise miss.In episode five of Neural Compass, Dr. Childs shares how we can use data to close equity gaps, personalize treatment, and design systems that actually serve the people in them.They cover:- What measurement-based care really looks like in practice- How Dr. Childs built a tool to reduce clinician burnout and improve outcomes- Why the future of behavioral health must include caregiver voices- The entrepreneurial lessons she learned turning a “flip-flop budget” into system-wide changeLearn more: jiminihealth.com No No What Happens When a Patient Works with Both a Therapist and AI? with Jon Tippens https://podcasts.fame.so/e/1n2r734n What Happens When a Patient Works with Both a Therapist and AI? with Jon Tippens 4 No No 2199nz71 "What if therapy didn’t just happen once a week—but became something you practiced every day?"In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Jon Tippens, a software engineer, musician, and Jimini patient, to explore how technology is reshaping the way we experience mental health care. Jon shares his deeply personal story as one of the first Jimini patients to go public about his experience—what changed when he started using Sage, Jimini’s AI companion, alongside human therapy, and how that shift transformed his understanding of what “effective therapy” can look like. With humor, insight, and a powerful metaphor from music education, Jon offers a new model: one where real growth comes from daily, meaningful engagement, not just 45 minutes a week.They cover:- Why real therapeutic change can happen between sessions—not just during them- The power of conversational journaling and AI-augmented reflection- How lowering friction can make mental health care more consistent and effective- Why it can feel easier to open up to a machine than a person- A new way to think about therapy as skill-building, not just storytellingLearn more: jiminihealth.com "What if therapy didn’t just happen once a week—but became something you practiced every day?"

In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Jon Tippens, a software engineer, musician, and Jimini patient, to explore how technology is reshaping the way we experience mental health care. Jon shares his deeply personal story as one of the first Jimini patients to go public about his experience—what changed when he started using Sage, Jimini’s AI companion, alongside human therapy, and how that shift transformed his understanding of what “effective therapy” can look like. With humor, insight, and a powerful metaphor from music education, Jon offers a new model: one where real growth comes from daily, meaningful engagement, not just 45 minutes a week.

They cover:

- Why real therapeutic change can happen between sessions—not just during them

- The power of conversational journaling and AI-augmented reflection

- How lowering friction can make mental health care more consistent and effective

- Why it can feel easier to open up to a machine than a person

- A new way to think about therapy as skill-building, not just storytelling

Learn more: jiminihealth.com

]]> Tue, 10 Jun 2025 13:01:00 +0000 Jimini Health Jimini Health 2470 "What if therapy didn’t just happen once a week—but became something you practiced every day?"In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Jon Tippens, a software engineer, musician, and Jimini patient, to explore how technology is reshaping the way we experience mental health care. Jon shares his deeply personal story as one of the first Jimini patients to go public about his experience—what changed when he started using Sage, Jimini’s AI companion, alongside human therapy, and how that shift transformed his understanding of what “effective therapy” can look like. With humor, insight, and a powerful metaphor from music education, Jon offers a new model: one where real growth comes from daily, meaningful engagement, not just 45 minutes a week.They cover:- Why real therapeutic change can happen between sessions—not just during them- The power of conversational journaling and AI-augmented reflection- How lowering friction can make mental health care more consistent and effective- Why it can feel easier to open up to a machine than a person- A new way to think about therapy as skill-building, not just storytellingLearn more: jiminihealth.com "What if therapy didn’t just happen once a week—but became something you practiced every day?"In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Jon Tippens, a software engineer, musician, and Jimini patient, to explore how technology is reshaping the way we experience mental health care. Jon shares his deeply personal story as one of the first Jimini patients to go public about his experience—what changed when he started using Sage, Jimini’s AI companion, alongside human therapy, and how that shift transformed his understanding of what “effective therapy” can look like. With humor, insight, and a powerful metaphor from music education, Jon offers a new model: one where real growth comes from daily, meaningful engagement, not just 45 minutes a week.They cover:- Why real therapeutic change can happen between sessions—not just during them- The power of conversational journaling and AI-augmented reflection- How lowering friction can make mental health care more consistent and effective- Why it can feel easier to open up to a machine than a person- A new way to think about therapy as skill-building, not just storytellingLearn more: jiminihealth.com No No Are We Treating Anxiety While Ignoring Avoidance? with Dr. Luana Marques https://podcasts.fame.so/e/68r7vkln Are We Treating Anxiety While Ignoring Avoidance? with Dr. Luana Marques 3 No No 805r5z81 What if anxiety isn’t the problem—but how we respond to it is? In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Dr. Luana Marques, Harvard psychologist and author of Bold Move, to reframe how we think about anxiety, avoidance, and the science of behavioral change.They cover:- Why anxiety isn’t the enemy- Practical tools for breaking fear-avoidance cycles- The connection between behavioral activation and success- How clinical insights apply to leadership, performance, and changeLearn more: jiminihealth.com What if anxiety isn’t the problem—but how we respond to it is? In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Dr. Luana Marques, Harvard psychologist and author of Bold Move, to reframe how we think about anxiety, avoidance, and the science of behavioral change.

They cover:

- Why anxiety isn’t the enemy

- Practical tools for breaking fear-avoidance cycles

- The connection between behavioral activation and success

- How clinical insights apply to leadership, performance, and change

Learn more: jiminihealth.com

]]> Tue, 27 May 2025 14:33:00 +0000 Jimini Health Jimini Health 2302 What if anxiety isn’t the problem—but how we respond to it is? In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Dr. Luana Marques, Harvard psychologist and author of Bold Move, to reframe how we think about anxiety, avoidance, and the science of behavioral change.They cover:- Why anxiety isn’t the enemy- Practical tools for breaking fear-avoidance cycles- The connection between behavioral activation and success- How clinical insights apply to leadership, performance, and changeLearn more: jiminihealth.com What if anxiety isn’t the problem—but how we respond to it is? In this episode of Neural Compass, host Mark Jacobstein (co-founder and president of Jimini Health) sits down with Dr. Luana Marques, Harvard psychologist and author of Bold Move, to reframe how we think about anxiety, avoidance, and the science of behavioral change.They cover:- Why anxiety isn’t the enemy- Practical tools for breaking fear-avoidance cycles- The connection between behavioral activation and success- How clinical insights apply to leadership, performance, and changeLearn more: jiminihealth.com No No Beyond Placebo: Is the Brain Our Most Powerful Medicine? with Dr. Asya Rolls https://podcasts.fame.so/e/1833p6v8 Beyond Placebo: Is the Brain Our Most Powerful Medicine? with Dr. Asya Rolls 2 No No m0jpl7r0 How does the placebo effect work in the brain and body? The brain can jumpstart your immune system, and science is finally catching up.In our second episode of Neural Compass, we explore one of the most mind-blowing frontiers in health: the connection between belief, biology, and the brain’s role in healing. Host Mark Jacobstein sits down with Dr. Asya Rolls — award-winning neuroscientist and professor of neuroimmunology — to discuss how the placebo effect isn’t just psychological… it’s physiological.They cover:- How the brain can activate the immune system- The neuroscience behind placebo, hope, and healing- Why the brain may be a key switch for turning on health- What it means to measure — and harness — the will to get betterLearn more: jiminihealth.com How does the placebo effect work in the brain and body? The brain can jumpstart your immune system, and science is finally catching up.

In our second episode of Neural Compass, we explore one of the most mind-blowing frontiers in health: the connection between belief, biology, and the brain’s role in healing. Host Mark Jacobstein sits down with Dr. Asya Rolls — award-winning neuroscientist and professor of neuroimmunology — to discuss how the placebo effect isn’t just psychological… it’s physiological.

They cover:

- How the brain can activate the immune system

- The neuroscience behind placebo, hope, and healing

- Why the brain may be a key switch for turning on health

- What it means to measure — and harness — the will to get better

Learn more: jiminihealth.com

]]> Tue, 27 May 2025 14:32:00 +0000 Jimini Health Jimini Health 2481 How does the placebo effect work in the brain and body? The brain can jumpstart your immune system, and science is finally catching up.In our second episode of Neural Compass, we explore one of the most mind-blowing frontiers in health: the connection between belief, biology, and the brain’s role in healing. Host Mark Jacobstein sits down with Dr. Asya Rolls — award-winning neuroscientist and professor of neuroimmunology — to discuss how the placebo effect isn’t just psychological… it’s physiological.They cover:- How the brain can activate the immune system- The neuroscience behind placebo, hope, and healing- Why the brain may be a key switch for turning on health- What it means to measure — and harness — the will to get betterLearn more: jiminihealth.com How does the placebo effect work in the brain and body? The brain can jumpstart your immune system, and science is finally catching up.In our second episode of Neural Compass, we explore one of the most mind-blowing frontiers in health: the connection between belief, biology, and the brain’s role in healing. Host Mark Jacobstein sits down with Dr. Asya Rolls — award-winning neuroscientist and professor of neuroimmunology — to discuss how the placebo effect isn’t just psychological… it’s physiological.They cover:- How the brain can activate the immune system- The neuroscience behind placebo, hope, and healing- Why the brain may be a key switch for turning on health- What it means to measure — and harness — the will to get betterLearn more: jiminihealth.com No No Can I Trust an AI Therapist? with Dr. Lyle Ungar https://podcasts.fame.so/e/286qv4wn Can I Trust an AI Therapist? with Dr. Lyle Ungar 1 No No j12r3zj1 AI can detect your depression. And we have the data to prove it. In our DEBUT episode of Neural Compass, we're kicking things off with a conversation that gets right to the heart of what this show is about — the intersection of AI, clinical care, and the future of mental and behavioral health. Host Mark Jacobstein sits down with Dr. Lyle Ungar — professor at UPenn and expert in machine learning, psychology, and language — to explore how AI is reshaping how we understand and care for the mind.They cover:
- How language models are being used to pre-screen for depression
 - The role of "synthetic friends" and when AI becomes too much of a crutch
- What it takes to move from mental illness to mental flourishing
- The future of AI-human collaboration in therapyLearn more: jiminihealth.com AI can detect your depression. And we have the data to prove it.

In our DEBUT episode of Neural Compass, we're kicking things off with a conversation that gets right to the heart of what this show is about — the intersection of AI, clinical care, and the future of mental and behavioral health. Host Mark Jacobstein sits down with Dr. Lyle Ungar — professor at UPenn and expert in machine learning, psychology, and language — to explore how AI is reshaping how we understand and care for the mind.

They cover:


- How language models are being used to pre-screen for depression


- The role of "synthetic friends" and when AI becomes too much of a crutch


- What it takes to move from mental illness to mental flourishing


- The future of AI-human collaboration in therapy

Learn more: jiminihealth.com

]]> Tue, 27 May 2025 13:01:00 +0000 Jimini Health Jimini Health 2680 AI can detect your depression. And we have the data to prove it. In our DEBUT episode of Neural Compass, we're kicking things off with a conversation that gets right to the heart of what this show is about — the intersection of AI, clinical care, and the future of mental and behavioral health. Host Mark Jacobstein sits down with Dr. Lyle Ungar — professor at UPenn and expert in machine learning, psychology, and language — to explore how AI is reshaping how we understand and care for the mind.They cover:
- How language models are being used to pre-screen for depression
 - The role of "synthetic friends" and when AI becomes too much of a crutch
- What it takes to move from mental illness to mental flourishing
- The future of AI-human collaboration in therapyLearn more: jiminihealth.com AI can detect your depression. And we have the data to prove it. In our DEBUT episode of Neural Compass, we're kicking things off with a conversation that gets right to the heart of what this show is about — the intersection of AI, clinical care, and the future of mental and behavioral health. Host Mark Jacobstein sits down with Dr. Lyle Ungar — professor at UPenn and expert in machine learning, psychology, and language — to explore how AI is reshaping how we understand and care for the mind.They cover:
- How language models are being used to pre-screen for depression
 - The role of "synthetic friends" and when AI becomes too much of a crutch
- What it takes to move from mental illness to mental flourishing
- The future of AI-human collaboration in therapyLearn more: jiminihealth.com No No Neural Compass - Trailer https://podcasts.fame.so/e/0njy54x8 Neural Compass - Trailer 0 No No 40pq97p1 Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com Welcome to Neural Compass, a new podcast from Jimini Health.

We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.

Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.

Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.

Learn more: jiminihealth.com

]]> Thu, 22 May 2025 12:56:00 +0000 Jimini Health Jimini Health 37 Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com Welcome to Neural Compass, a new podcast from Jimini Health.We’re charting the future of mental and behavioral health — at the intersection of AI, psychiatry, neuroscience, and real-world clinical care.Hosted by Jimini’s own Mark Jacobstein, Neural Compass features honest, forward-thinking conversations with the leaders shaping what’s next — from healthcare executives to AI pioneers.Whether you’re building in this space, investing in it, or navigating it as a decision-maker, this podcast is your guide to the breakthroughs, challenges, and ideas defining the next era of care.Learn more: jiminihealth.com No No